Visual Proteomics Imaging

About this funding opportunity

This RFA closed on February 17, 2021

SCIENCE GRANT RESOURCES PAGE Visual Proteomics Imaging

The Chan Zuckerberg Initiative invites applications for challenge grants in the field of Visual Proteomics. This Request for Applications (RFA) aims to advance technology directed at the goal of obtaining near-atomic resolution readouts inside the cell. Learn about our grantees and watch our video with WIRED").

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For administrative and programmatic inquiries, technical assistance, or other questions pertaining to this RFA, please contact sciencegrants@chanzuckerberg.com. Key Dates

December 2, 2020

Application portal opens

February 17, 2021

Applications due by 5 p.m. Pacific Time (PT)

May 2021

Earliest notification of decisions (subject to change)

August 1, 2021

Earliest start date (subject to change)

Award period and start date: Awards will be 2.5 years (30 months) in duration with a start date of no earlier than August 1, 2021. Actual start date may vary.

Important Documents:

Application Instructions")

Institutional Approval Form") Opportunity

Overview

The Chan Zuckerberg Initiative (CZI) seeks to support 2.5-year challenge grants in the field of visual proteomics. The ability to view protein molecules in cells and monitor changes in their structure, quantity, distribution, and interactions is key to understanding what causes diseases and finding treatments and cures. This grant program will advance technology development for the field of visual proteomics and aim to obtain near-atomic resolution readouts inside the cell. The funding mechanism will be targeted investments in the form of challenge grants with specified proof-of-concept milestones.

Scientific Scope

The long-term goal of this RFA, part of CZI’s Frontiers of Imaging effort, is to drive technology development aimed at visualizing proteins and their interactions inside the cell. This funding opportunity is explicitly aimed at technology development. It is not intended to support question-driven basic or translational research, clinical trials, or drug development. Preliminary data is encouraged but not required.

Examples of research themes: Hardware and software development to enhance contrast and resolution for electron tomography, high-resolution correlated light and electron microscopy (CLEM), and FIB-SEM. Sample preparation improvements for electron tomography, or high-resolution correlated light and electron microscopy (CLEM) approaches, and FIB-SEM. Software development or development of new computational techniques and algorithms for identifying protein molecules inside cells or segmenting cellular sub-structures.

We particularly encourage applications from: Researchers in disciplines outside of biomedicine who bring new technology, resources, or frameworks to studying proteins and their interactions inside of cells; Women, underrepresented minorities, and members of underserved populations; and Early-career investigators, defined as principal investigators who have been in an independent faculty role for less than six years at the time of application, i.e. starting after their first position after February 2015.

Desired Outcomes

Successful outcomes for this RFA could include: Development of hardware and software that will enhance contrast and resolution; Development of hardware, software, or methods that will improve sample preparation; and Development of new computational techniques and algorithms for identifying protein molecules inside cells.

Collaboration and Open Science

CZI seeks investigators who will contribute to a collaborative interdisciplinary network and the advancement of the visual proteomics field. Investigators and members of their labs will participate in annual meetings of all funded groups, smaller meetings focused on specific biological or technical topics, and regular webinars. Investigators and CZI staff will work together to identify resources and technology…

Topic areas: Life Sciences and Health, General and Cross-cutting R&D.

Funding amount

This grant provides Varies in funding.

Deadline

Applications are accepted on a rolling basis; there is no single fixed deadline.

Who can apply

This opportunity is open to the following applicant types:

• Not specified by the program.

Eligibility

The program did not publish a separate eligibility statement. See the official opportunity page for the full eligibility criteria.

Agency

Visual Proteomics Imaging is administered by Chan Zuckerberg Initiative (CZI), listed via Chan Zuckerberg Initiative.