Single-Cell Biology Data Insights

About this funding opportunity

This RFA closed on December 5, 2023

SCIENCE GRANT RESOURCES PAGE Data Insights Cycle 3

The Chan Zuckerberg Initiative invites applications for the third of three cycles for 18-month projects focused on advancing tools and resources that make it possible to gain greater insights into health and disease from single-cell biology datasets. Learn about our grantees from Cycle 1") and view the RFA"). Learn about our grantees from Cycle 2") and view the RFA"). Learn about our grantees from Cycle 3 and view the RFA.")

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For administrative and programmatic inquiries, or other questions pertaining to this RFA, please contact sciencegrants@chanzuckerberg.com. Key Dates

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We invite applications for consideration for funding during three distinct cycles:

September 19, 2023

Cycle 3 Application opening date

December 5, 2023

Cycle 3 Applications due by 5 p.m. Pacific Time

Late June 2024

Cycle 3 Earliest notification of decisions (subject to change)

August 1, 2024

Cycle 3 Earliest start date (subject to change)

Award period and start date: Proposed projects should be 18 months; expected start date for awards in Cycle 3 is August 1, 2024.

IMPORTANT DOCUMENTS:

Application Instructions")

Institutional Approval Form") Opportunity

Overview

The Chan Zuckerberg Initiative (CZI) seeks to support projects that will advance the fields of single-cell biology and data science. Grantees will be expected to interact with existing groups to build community and accelerate progress. Applications are encouraged from computational experts outside the field of single-cell biology, but with expertise relevant to overcoming current bottlenecks and driving discoveries in the single-cell biology field. Projects may include: dedicated efforts to democratize access and usability of existing datasets; demonstration of utility by leveraging existing datasets to address impactful and challenging biological questions; and developing methods that enable greater biological insight and other major challenges brought forward. This request for applications is the last of three currently planned cycles, with successful projects receiving 18 months of funding support.

Scope

Applications for two types of grants are welcome and will be reviewed independently. The maximum budgets for proposed projects are $400,000 total costs for _Expanded Projects_ and $200,000 total costs for _Focused Projects_. All project awards will be for an 18-month duration. The goal of this opportunity is to create a network of projects that address broad computational challenges and needs within single-cell biology at a variety of scales. Applicants may highlight existing or prospective collaboration among projects, but should note that all applications will be reviewed for their individual merit and impact.

Single-cell biology has undergone rapid growth over the last five years, with a recent increase in the volume of available and openly accessible datasets and cell atlases, including the release of the 37+ million cells CZ CELLxGENE Discover Census"). This funding opportunity is specifically intended to motivate and incentivize the development, refinement, and implementation of approaches that make it possible for greater insights to be gained from available single-cell data. With this in mind, any form of data generation is considered out of scope. Projects must propose and rely on existing data that is openly and freely available (count matrices at minimum) at the time of application via the inclusion of a link to specific datasets in the applications. Furthermore, we strongly encourage applications to use data generated outside of their labs to enable interoperability and advances that are extensible to a wider segment of interested researchers.

Addressing computational challenges and bottlenecks in single-cell biology will drive the field forward and make it possible for a greater number of scientists to…

Topic areas: Life Sciences and Health, General and Cross-cutting R&D.

Funding amount

This grant provides Varies in funding.

Deadline

Applications are accepted on a rolling basis; there is no single fixed deadline.

Who can apply

This opportunity is open to the following applicant types:

• Not specified by the program.

Eligibility

The program did not publish a separate eligibility statement. See the official opportunity page for the full eligibility criteria.

Agency

Single-Cell Biology Data Insights is administered by Chan Zuckerberg Initiative (CZI), listed via Chan Zuckerberg Initiative.