Partnering Research and Community Organizations for Comparative Clinical Effectiveness Research Across the Cancer Care Continuum PCORI Funding Announcement (The Cancer Partner PFA) -- Cycle 1 2026

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Applications Under Review Partnering Research and Community Organizations for Comparative Clinical Effectiveness Research Across the Cancer Care Continuum PCORI Funding Announcement (The Cancer Partner PFA) -- Cycle 1 2026

Research

Cycle 1 2026 Key Information/Dates PFA Opened

Dec. 2, 2025 Preannouncement Town Hall

View recording/slides Applicant Town Hall

View recording/slides Letter of Intent (LOI) Deadline

Jan. 6, 2026; 5 pm (ET) LOI Status Notification

Feb. 3, 2026 Application Deadline

May. 5, 2026; 5 pm (ET)

Apply Here")

This PCORI Funding Announcement seeks to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects led by researcher and community partnerships to focus on advancing care and outcomes across different phases of the cancer care continuum. Proposed CER projects should inform health decisions for patients, caregivers and communities in the United States experiencing high burdens and practice variations in cancer care and outcomes. Research Initiative Highlights

Approximately 40% of people in the United States are expected to be diagnosed with cancer during their lifetimes. Advances in early detection and cancer treatments have resulted in an increased ability to identify and treat individuals affected by cancer. Despite such advances, cancer and its treatments continue to have both short- and long-term physical, emotional, social, and financial impacts on the lives of patients and their caregivers. Furthermore, specific subgroups of the U.S. population bear a greater burden of cancer. Variations in cancer care and outcomes exist due to several factors, including geography, age, income, and stage of illness. These variations exist throughout the entire cancer continuum, spanning prevention, screening, diagnosis, treatment, survivorship, and palliative and end-of-life care. To address such variations, recent reports have underscored the need for intentional collaborations between community organizations, researchers, health systems, and other stakeholders and have called for the implementation of community-based solutions to meet the…

Topic areas: Life Sciences and Health, Public Policy and Governance, Social Innovation and Community Development.

Funding amount

This grant provides Varies in funding.

Deadline

Applications are accepted on a rolling basis; there is no single fixed deadline.

Who can apply

This opportunity is open to the following applicant types:

• Not specified by the program.

Eligibility

The program did not publish a separate eligibility statement. See the official opportunity page for the full eligibility criteria.

Agency

Partnering Research and Community Organizations for Comparative Clinical Effectiveness Research Across the Cancer Care Continuum PCORI Funding Announcement (The Cancer Partner PFA) -- Cycle 1 2026 is administered by Patient-Centered Outcomes Research Institute (PCORI), listed via Patient-Centered Outcomes Research Institute.