Mission Boost Grants (MBG)

About this funding opportunity

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Research We Fund: Extramural Discovery Science (EDS) Apply for a Research Grant

[x] - Grant Types

[x] - ACS Professor Award Arizona (AZ) Discovery Boost Grants (DBG) ASTRO-ACS Clinician Scientist Development Grant (CSDG) Clinician Scientist Development Grant (CSDG) Discovery Boost Grants (DBG) HEALED Gold Medal RFA To Support Mind-Body-Spirit Wellness in Cancer Survivors Institutional Research Grants Mission Boost Grants (MBG) Postdoctoral Fellowships Research Scholar Grants RFA: Extramural Discovery Science Accelerator Award RFA: Leukemia Exploration and Prevention Grant Program (LEAP) TheoryLab Collaborative (TLC) Grant RFA: Cancer Health Research Centers (CHERCs) RFA: Biology to Prevention Award (CRUK) RFA: ACS - Fanconi Cancer Foundation Discovery Boost Grant RFA: American Cancer Society Catalyst Awards RFA: American Cancer Society - Flatiron Real-World Data Impact Award RFA: Yosemite-American Cancer Society Award Extramural Grants Department Staff Contacts Definition of Research Areas FAQs: ACS Extramural Discovery Science and Grant Application Submissions Extramural Priority Research Areas Our Grant Process Summer 2026 Grant Cycle: Summary of Changes American Cancer Society Research Events EDS: Our Research Programs

[] - Career Growth and Research Excellence Program

[] - ACS Professor Cancer Detection and Experimental Therapeutics (PF-CDET) Institutional Research Grants (IRG) Cell Biology and Immunology (PF-CBI) Clinical and Population Sciences (PF-CPS) Molecular Biology and Biochemistry (PF-MBB) Biochemistry and Immunology of Cancer Program

[] - DNA Mechanisms in Cancer (DMC) PRC Immunology and Blood Cell Development (IBCD) PRC RNA Mechanisms in Cancer (RMC) PRC Tumor Biochemistry and Endocrinology (TBE) PRC Mission Boost Grants (MBG) PRC Cell Biology and Preclinical Cancer Research Program

[] - Cancer Cell Biology (CCB) PRC Cancer Detection and Progression (CDP) PRC Experimental Therapeutics (ET) PRC Metastasis and Microenvironment (MM) PRC Clinical and Population Sciences Program

[] - Cancer Prevention and Health Promotion (CPHP) PRC Treatment, Palliative Care, and Survivorship Research (CTPS) Etiology, Screening, and Early Detection (ESED) Healthcare Outcomes, Policy, and Systems Research (HOPS) Peer Review Committees (PRCs)

[] - Discovery Scientific Council Community Research Partner Participation American Cancer Society Professors Nobel Laureates and the American Cancer Society American Cancer Society-Jiler Professors & Fellows Conference Mission Boost Grants (MBG) Grant Overview

Mission Boost Grants (MBG) are designed to support research projects that specifically focus on translation to human testing. MBGs are opportunities for independent investigators at all levels to apply for additional, or "boost," resources for innovative, clinical-enabling projects.

MBGs offer 2 stages of funding: Stage I requires the investigator to develop outcome-specific, unequivocal milestones that reduce the risks of studying a new drug, device, or procedure in patients. Stage II supports testing in cancer patients. Eligibility Stage I Mission Boost

We no longer require MBG applicants to be current or former ACS grantees or fellows. Starting in 2025, you ARE eligible to submit a proposal if you: Work at an academic institution in the United States or eligible nonprofit Are an independent investigator with a full-time faculty appointment (or equivalent). Applicants may be at any career stage. Applicants may submit only one MBG I or MBG II application per cycle, and applicants may not submit RSG, DBG, or CSDG applications in the same cycle as a MBG submission. Stage II Mission Boost

You ARE eligible to submit a proposal if you: Work at an academic institution in the United States or eligible nonprofit Are an independent investigator with a full-time faculty appointment (or equivalent). Applicants may be at any career stage. Previously held or currently hold a…

Topic areas: Life Sciences and Health.

Funding amount

This grant provides Varies in funding.

Deadline

Applications are accepted on a rolling basis; there is no single fixed deadline.

Who can apply

This opportunity is open to the following applicant types:

• Not specified by the program.

Eligibility

The program did not publish a separate eligibility statement. See the official opportunity page for the full eligibility criteria.

Agency

Mission Boost Grants (MBG) is administered by American Cancer Society (ACS), listed via American Cancer Society.