Innate Immune System Impact Request for Applications, Ph.D.

About this funding opportunity

Search SFARI Home Funding Application Deadline

March 3, 2014 Notification of Award

July 1, 2014 Funding Expected to Begin

August 1, 2014 SFARI Grant Programs

sciencerfa@simonsfoundation.org Application Deadline

March 3, 2014 Notification of Award

July 1, 2014 Funding Expected to Begin

August 1, 2014 SFARI Grant Programs

sciencerfa@simonsfoundation.org

Grants awarded through this request for applications (RFA) were intended to advance our understanding of the impact of activation of the innate immune system on behavioral, circuit, synaptic and neuronal functions in order to understand the consequences of infection and immune activation on autism-related behaviors.

To this end, we sought applications for investigations of the impact of physiologically relevant activation of the innate immune system on behavioral, circuit, synaptic and neuronal functions in animal models of autism. SFARI especially encouraged applications that address either of the following two issues:

(1) Effects of activation of the maternal innate immune system on embryonic central nervous system development in genetic models of autism and controls. How do fetal genetics and maternal innate immune activation interact to affect postnatal autism-related phenotypes, and what are the mechanisms through which they interact?

(2) Effects of activation of the innate immune system in genetic autism models and adult controls. How does innate immune activation affect behavioral, circuit, synaptic and cellular function in these genetic models and in controls? What are the roles of cytokine signaling, fever, immune cell activation and other effectors on these functions? Application Deadline

March 3, 2014 Notification of Award

July 1, 2014 Funding Expected to Begin

August 1, 2014 SFARI Grant Programs

sciencerfa@simonsfoundation.org Instructions for submission

Applications must be completed electronically and submitted using forms provided at proposalCENTRAL. Please log in as an applicant, scroll to ‘Simons Foundation’ and click on the program. Con tacts Scientific inquiries: sciencerfa@simonsfoundation.org 646-654-0066 Administrative inquiries: grants@simonsfoundation.org 646-654-0066 proposalCENTRAL: pcsupport@altum.com 800-875-2562 Application Deadline

March 3, 2014 Notification of Award

July 1, 2014 Funding Expected to Begin

August 1, 2014 SFARI Grant Programs

sciencerfa@simonsfoundation.org Frequently Asked Questionsplus--large

How do I submit a full proposal?plus--large

New users first need to register on proposalCENTRAL. For all users, log in and select “Create New Proposal” or click on the “Grant Opportunities” tab. Filter the Grant Maker by “Simons Foundation” and click on “Apply Now” next to the “Innate Immune System Impact” program. Once all sections are complete and the attachments are uploaded, the “Submit” button will be activated.

Are references, figures and figure legends included in the narrative six (6)-page limit? How should they be included?plus--large

References, figures and figure legends are not included in the page limit for the full proposal. Please attach them at the end of the six (6)-page narrative in the same PDF file. The Simons Foundation’s preference is for figures to follow the narrative rather than be embedded in the text.

What are the font and size requirements?plus--large

11-point, legible font.

What can I include as an appendix?plus--large

‘In-press’ papers can be included as appendices, as well as any papers that you consider essential for the work of the review committee (not more than three [3]). Any other material should be included, if possible, in the narrative. If you have video attachments for your proposal, please upload as an appendix (all file types are accepted).

How can I find out more about available biospecimens and other data available from the Simons Variation in Individuals Project (Simons VIP) and Simons Simplex Collection (SSC)?plus--large

You can access and request information about…

Topic areas: Life Sciences and Health.

Funding amount

This grant provides Varies in funding.

Deadline

Applications are accepted on a rolling basis; there is no single fixed deadline.

Who can apply

This opportunity is open to the following applicant types:

• Not specified by the program.

Eligibility

The program did not publish a separate eligibility statement. See the official opportunity page for the full eligibility criteria.

Agency

Innate Immune System Impact Request for Applications, Ph.D. is administered by Simons Foundation (Simons), listed via Simons Foundation.