Genomic Analysis for Autism Risk Variants in SPARK, Request for Applications

About this funding opportunity

Search SFARI Home Funding Application Available

May 21, 2018 Notice of Intent Deadline

June 22, 2018 Full Proposal Deadline

July 27, 2018 Award Notification

November 14, 2018 Award Start Date

December 1, 2018 Scientific Inquiries

sciencerfa@simonsfoundation.org

646-654-0066 Administrative Inquiries

grants@simonsfoundation.org

646-654-0066 SPARK Data and Recruitment Questions

collections@sfari.org

646-654-0066 Application Available

May 21, 2018 Notice of Intent Deadline

June 22, 2018 Full Proposal Deadline

July 27, 2018 Award Notification

November 14, 2018 Award Start Date

December 1, 2018 Scientific Inquiries

sciencerfa@simonsfoundation.org

646-654-0066 Administrative Inquiries

grants@simonsfoundation.org

646-654-0066 SPARK Data and Recruitment Questions

collections@sfari.org

646-654-0066

SPARK (Simons Foundation Powering Autism Research) is an autism research initiative that aims to recruit, engage and retain a community of 50,000 individuals with autism and their family members living in the U.S. Participation in this cohort involves contribution of medical and behavioral information, mailing in of saliva for genetic analysis, the option to have genetic findings related to autism returned, and consent to be invited to participate in future research studies.

This request for applications sought proposals that will advance our understanding of the genetic basis of autism using data from SPARK. SFARI welcomed proposals that focus on any type of genetic variants (rare and common variants, single-nucleotide variants (SNVs), copy number variants (CNVs), indels, coding and noncoding variants) that contribute to autism risk. We encouraged innovative applications that combine analyses of variants across the allele frequency spectrum. We prioritized proposals that analyzed SPARK data in conjunction with available genomic data from other ASD and neurodevelopmental genetic cohorts.

SFARI made the alignment and variant call data available to all eligible researchers (i.e., not only those funded through this RFA) following standard quality control and data processing steps.

SFARI worked with successful applicants to make the genomic data available to their academic or cloud-based computing resources. SFARI understood that validation of _de novo_ variants in recurrent genes/pathways is a key aspect of this project and coordinated experimental confirmation of _de novo_ calls with awardees. Application Available

May 21, 2018 Notice of Intent Deadline

June 22, 2018 Full Proposal Deadline

July 27, 2018 Award Notification

November 14, 2018 Award Start Date

December 1, 2018 Scientific Inquiries

sciencerfa@simonsfoundation.org

646-654-0066 Administrative Inquiries

grants@simonsfoundation.org

646-654-0066 SPARK Data and Recruitment Questions

collections@sfari.org

646-654-0066

The deadline for application submission is Friday, July 27, 2018, at 5 p.m. EDT.

proposalCENTRAL Login Information

Prospective applicants must submit an application via proposalCENTRAL (pC). To start an application in pC, users must first login to their pC account.

If You Need to Create a New Account in pC

To create a new account, go to proposalCENTRAL and click CREATE ONE NOW under APPLICATION LOGIN. Fill in the required fields, check the boxes to agree to pC’s “Terms of Service” and “Acceptable Use Policy” and then click SAVE.

If You Have an Existing Account in pC

For all users with a pC account, log in under APPLICATION LOGIN at proposalCENTRAL and select CREATE NEW PROPOSAL or click on the GRANT OPPORTUNITIES tab. Scroll down to SIMONS FOUNDATION and then click APPLY NOW for the “Simons Foundation Autism Research Initiative, Genomic Analysis for Autism Risk Variants in SPARK” program in order to start the proposal and access the templates. After all sections are completed, you will be able to click on the SUBMIT button to send.

To submit a full application, the following proposalCENTRAL sections must be completed: Title Page:…

Topic areas: Life Sciences and Health.

Funding amount

This grant provides Varies in funding.

Deadline

Applications are accepted on a rolling basis; there is no single fixed deadline.

Who can apply

This opportunity is open to the following applicant types:

• Not specified by the program.

Eligibility

The program did not publish a separate eligibility statement. See the official opportunity page for the full eligibility criteria.

Agency

Genomic Analysis for Autism Risk Variants in SPARK, Request for Applications is administered by Simons Foundation (Simons), listed via Simons Foundation.