Deep Tissue Imaging (Phases 1-2)

About this funding opportunity

This RFA closed on July 11, 2023

SCIENCE GRANT RESOURCES PAGE Deep Tissue Imaging (Phase 2)

The Chan Zuckerberg Initiative (CZI) invites applications for four-year projects in the field of deep tissue imaging. To gain a deeper mechanistic understanding of biological systems, CZI’s Imaging program aims to visualize and measure them across biological scales and in their biological context. This Request for Applications (RFA) seeks to drive development of imaging technology focused on obtaining cellular resolution readouts within complex living organisms. This grant program will advance the field of deep tissue imaging, which aims to obtain cellular resolution in complex tissue and through skin and bone. Learn about our Phase 2 grantees, Phase 1 grantees") and view the Phase 1 RFA"), read our Medium post"), and watch our video with WIRED").

Download RFA Packet\\ \\ (Opens in a new window) RFA Contact

For administrative and programmatic inquiries, technical assistance, or other questions pertaining to this RFA, please contact sciencegrants@chanzuckerberg.com"). Key Dates

May 18, 2023

Application portal opens to receive Letters of Intent

July 11, 2023

Letters of Intent due by 5 p.m. Pacific Time

By August 15, 2023

Notification for invitation to submit Full Applications

September 26, 2023

Full Applications due by 5 p.m. Pacific Time

January 2024

Earliest notification of decisions (subject to change)

March 1, 2024

Expected start date (subject to change) Opportunity

The Phase 2 RFA is a two-step application process. We invite letters of intent (LOI) where applicants will provide a short proposal detailing the current state of a deep tissue imaging technology and how their project will advance this technology. A subset of the LOI applicants will be invited to submit a full application for four-year projects.

To accelerate recent innovations in deep tissue imaging technology development, this Phase 2 RFA is open to all applicants, as detailed in the Eligibility section below. Phase 2 is not limited to Deep Tissue Imaging Phase 1") pilot projects or investigators. Applications from Phase 1 pilot project grantees may 1) continue development of their Phase 1 project, 2) modify or expand the scope of their Phase 1 project, or 3) propose a new project.

Scientific Scope

The long-term goal of this opportunity is to drive technology development aimed at visualizing cellular structure and function throughout the body. We especially seek proposals that support the development of tools for visualizing cellular-level processes in deep tissue. This funding opportunity is explicitly aimed at technology development. It is not intended to support question-driven basic or translational research, clinical trials, or drug development.

Examples of research themes: Adaptive optics for deep tissue imaging Bioacoustic probe, hardware, and/or method development Biomagnetic probe, hardware, and/or method development Biochemical probe or method development Multi-photon hardware or method development Quantum technologies for deep tissue imaging Deep tissue imaging techniques with potential applicability to the human body

We particularly encourage applications from: Researchers in disciplines outside of biomedicine who bring new technology, resources, or frameworks to studying cellular processes; Women, those underrepresented or marginalized in science, and diverse groups worldwide; and Early career investigators, defined as principal investigators who have been in an independent faculty role for less than six years at the time of application, i.e. starting after July 11, 2017.

Desired Outcomes

Successful outcomes for this RFA could include: Development of biological probes to label cells and subcellular processes throughout the body; Development of technologies that enable imaging at cellular resolution anywhere in complex living organisms; or Development of new computational techniques and algorithms for relevant signal extraction and…

Topic areas: Life Sciences and Health.

Funding amount

This grant provides Varies in funding.

Deadline

Applications are accepted on a rolling basis; there is no single fixed deadline.

Who can apply

This opportunity is open to the following applicant types:

• Not specified by the program.

Eligibility

The program did not publish a separate eligibility statement. See the official opportunity page for the full eligibility criteria.

Agency

Deep Tissue Imaging (Phases 1-2) is administered by Chan Zuckerberg Initiative (CZI), listed via Chan Zuckerberg Initiative.