Collaborative Computational Tools for a Human Cell Atlas

About this funding opportunity

This RFA closed on August 28, 2017

SCIENCE GRANT RESOURCES PAGE Collaborative Computational Tools for the Human Cell Atlas

The Chan Zuckerberg Initiative invites applications for one-year projects to develop computational tools, algorithms, visualizations, and benchmark datasets in support of the Human Cell Atlas. Participants in this project will collaborate with each other and with CZI scientists and engineers to accelerate progress, facilitate communication, and maximize open dissemination of the resulting tools. Learn about our grantees and read our Medium post").

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For administrative and programmatic inquiries, technical assistance, or other questions pertaining to this RFA, please contact sciencegrants@chanzuckerberg.com. Key Dates

July 25, 2017

Application portal is open for registrations and applications

Aug 28, 2017

Applications due by 5:00 PM PT

Jan 15, 2018

Earliest notification of decisions (subject to change)

Feb 1, 2018

Earliest start date of project (subject to change)

Award period and start date: Proposed projects should be one year in duration with a projected start date no earlier than February 1, 2018. Actual start date may vary. Overview

The goal of the International Human Cell Atlas project is to create a shared, open reference atlas of all cells in the healthy human body as a resource for studies of health and disease. This endeavor will generate molecular and imaging data across a range of modalities and spatial scales, requiring new probabilistic and integrative approaches for analysis and interpretation, systematic comparison of methods on benchmark datasets, and mechanisms for disseminating these methods to a wide community. The Chan Zuckerberg Initiative seeks applications for the development of computational tools, algorithms, visualizations, and benchmark datasets in support of this endeavor. This program welcomes applicants who are new to the Human Cell Atlas, no prior work in this area is required. In a new approach to open, collaborative development, researchers on projects funded by these grants shall work together and share progress with each other to evaluate the strengths of different approaches. To maximize the impact and visibility of this work, members of the Chan Zuckerberg Initiative science and engineering teams will work with successful grant recipients to help enhance and package their tools, and link them to the Human Cell Atlas Data Coordination Platform (DCP), if appropriate and desired. Project Specifications

Many computational efforts in support of the Human Cell Atlas are underway in the research community, and new methods are needed. This RFA aims to support further development and systematic comparison of methods across existing and new benchmark datasets derived from single-cell RNA sequencing, bulk RNA sequencing, proteomics, image-based transcriptomics, and other tissue imaging approaches. The RFA will also support new analysis and visualization methods, and new approaches to integrating data across modalities. The goal is to support a diverse set of well-validated tools to analyze, consume, integrate, and explore Human Cell Atlas data.

To help the resulting tools reach the widest possible audience, scientists and engineers from the Chan Zuckerberg Initiative will collaborate with researchers on projects funded by this RFA to help bring tools to the scientific community; for example, by helping to enhance or package software with an emphasis on scale, robustness, speed, interoperability, web-based dissemination, and user experience. There will also be opportunities for new tools to connect to and leverage the Human Cell Atlas Data Coordination Platform") (https://www.humancellatlas.org/data-sharing), which provides infrastructure for data sharing and cloud computing.

This effort is also a pilot project for new models of collaborative computational research. With the assistance of the Chan…

Topic areas: Life Sciences and Health, General and Cross-cutting R&D.

Funding amount

This grant provides Varies in funding.

Deadline

Applications are accepted on a rolling basis; there is no single fixed deadline.

Who can apply

This opportunity is open to the following applicant types:

• Not specified by the program.

Eligibility

The program did not publish a separate eligibility statement. See the official opportunity page for the full eligibility criteria.

Agency

Collaborative Computational Tools for a Human Cell Atlas is administered by Chan Zuckerberg Initiative (CZI), listed via Chan Zuckerberg Initiative.