2026-27 Request for Proposals

About this funding opportunity

2025-2026 Request for Proposals

The Melanoma Research Alliance (MRA) is pleased to announce a Request for Proposals (RFP) for pre-clinical, translational, and early clinical research with the potential to produce unusually high impact, near-term advancements in melanoma prevention, detection, diagnosis, and treatment.

This cycle, proposals will be accepted for Team Science Awards, Academic-Industry Partnership Award (for Team Science Awards), Young Investigator Awards, and Pilot Awards.

MRA plans to support at least $11.5 million in new funding in the 2025-2026 cycle. Special Opportunities Included in RFP: Acral Melanoma Team Science, Young Investigator, and Pilot Awards focused on Advancing Translational Research for Acral Melanoma Uveal Melanoma Team Science, Young Investigator, and Pilot Awards focused on Advancing Translational Research for Uveal Melanoma Team Science, Young Investigator, and Pilot Awards from applicants based in the United Kingdom (UK) Team Science, Young Investigator, and Pilot Awards from applicants based in Israel Rising Tide Foundation for Clinical Cancer Research (RTFCCR)-MRA Team Science Award on Melanoma Early Detection, Diagnosis, and Risk Stratification

Please Note the Following Key Deadlines: September 25, 2025: Letters of Intent (LOI) due for Team Science Awards and Team Science Academic-Industry Partnership Award September 30, 2025: Eligibility Checklist and Biosketch due for Young Investigator Award applicants November 6, 2025: Proposals due for Young Investigator and Pilot Awards January 8, 2026: Invited Team Science Award full proposals due April 2026: Awardees notified of funding decisions June 1, 2026: Project Start Date

Key Deadlines for RTFCCR-MRA Special Opportunity Team Science Award ONLY: October 28, 2025: Letters of Intent (LOI) due February 2, 2026: Invited full applications due May 2026: Awardees notified of funding decisions June 1, 2026: Projects start

All proposals are due by 11:59 pm Eastern Time. Proposals should be submitted via the proposalCENTRAL online application tool: https://proposalcentral.com/

MRA 2025-26 RFP RTFCCR-MRA RFP

MRA Award Terms & Conditions

_MRA accepts proposals from researchers worldwide and encourages applications from a diverse pool of investigators with respect to race, gender, sexual orientation, ethnicity, national origin, country of residence, and disability. MRA recognizes that diversity in the biomedical research workforce is critical for ensuring that the most creative minds have the opportunity to contribute to realizing our research goals and to ensuring more equitable health outcomes for all._ Questions?

Please contact the MRA Science team at science@curemelanoma.org.

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A2A

Topic areas: Life Sciences and Health.

Funding amount

This grant provides Varies in funding.

Deadline

Applications are accepted on a rolling basis; there is no single fixed deadline.

Who can apply

This opportunity is open to the following applicant types:

• Not specified by the program.

Eligibility

The program did not publish a separate eligibility statement. See the official opportunity page for the full eligibility criteria.

Agency

2026-27 Request for Proposals is administered by Melanoma Research Alliance (MRA), listed via Melanoma Research Alliance.